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Cost-Effectiveness of Routine and Campaign Use of Typhoid Vi-Conjugate Vaccine in Gavi-Eligible Countries: A Modelling Study

This article, published in The Lancet Infectious Diseases, reports the results of a modelling study to evaluate the cost-effectiveness of typhoid conjugate vaccine in low- and middle-income countries with varying typhoid burdens. The study modelled four strategies: no vaccination, routine immunization at 9 months, and routine immunization at 9 months with catch-up campaigns to either age 5 years or 15 years of age. The results indicate that vaccination is likely to be cost-effective in countries with high typhoid incidence, high cost of typhoid treatment, and/or high death rates from typhoid. Furthermore, results indicate that it is always cost-effective to include a catch-up campaign when introducing routine typhoid vaccination.

Author: Bilcke J, Antillon M, Pieters Z, et al.

Published: 2019

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(Located at www.thelancet.com)

Citation: Bilcke J, Antillon M, Pieters Z, et al. Cost-Effectiveness of Routine and Campaign Use of Typhoid Vi-Conjugate Vaccine in Gavi-Eligible Countries: A Modelling Study. The Lancet Infectious Diseases. 2019;19(7):728-739.

Resource types: Peer-reviewed journal

Diseases/vaccines: Typhoid

Topics: Immunization financing, Disease/vaccine specific information

Regions: Global